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Conquer allergy season: Exploring safer antihistamines

Do you suffer from allergies? Long-term use of allergy medication requires a safer approach. Our partners at Optum Perks have identified the 5 safest antihistamines for continuous use.

Conquer allergy season: Exploring safer antihistamines

Finding Long-Term Relief: Exploring Safer Antihistamines

Cetirizine (Zyrtec) is a second-generation antihistamine doctors commonly prescribe to treat urticaria (hives) and inflammation in the nose. It works by blocking histamine, a substance released during an allergic reaction, which helps relieve allergy symptoms such as sneezing, itching, and runny nose.

Possible side effects include drowsiness, dry mouth, and headaches.

Loratadine (Claritin) is also a second-generation antihistamine that can help manage allergies and is available over the counter. It works by blocking the action of histamine to relieve allergy symptoms.

Common side effects are headaches, stomach upset, and dizziness.

Fexofenadine (Allegra) is a third-generation antihistamine that can help treat chronic itching and seasonal allergies. It can also improve symptoms resulting from an overactive immune response.

It is one of the least sedating antihistamines, making it a safe option for long-term use if you take it as your doctor prescribes.

Possible side effects may include, headaches, nose bleeds, nausea, and stomach discomfort.

Desloratadine (Clarinex) is a third-generation antihistamine that works by blocking the action of histamine and treating the nasal and non-nasal symptoms of seasonal allergies such as sneezing, runny nose, and watery eyes. It can also treat chronic urticaria, a type of itchy skin rash.

Possible side effects are dry mouth and fatigue.

Levocetirizine (Xyzal) is an antihistamine belonging to the third-generation drug class. Doctors prescribe it for symptoms of hives on the skin and hay fever.

Common side effects may include fatigue, drowsiness, weakness, and urinary retention.

At Union Plus, we understand the importance of keeping your family healthy and managing allergy symptoms effectively. While this article provided a brief overview of some common allergy medications, remember this is not a substitute for personalized medical advice. Please schedule an appointment with a healthcare professional to review the right options for you and your family.


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